Having recently incorporated ozone therapy as part of our Endodontic protocol, we would like to share with our patients some facts regarding ozone.
Ozone (O3) is an allotrope of Oxygen (O2). All allotrope is a variant of substance consisting of only one type of atom. It has a NEW molecular configuration and NEW PHYSICAL PROPERTIES.
Ozone is an oxidant and is also referred to as an oxidizer. An oxidizer is a substance that accepts an electron from another substance and is then reduced. It acts as an electron acceptor. It also adds an oxygen atom to the compound being oxidized. In vivo it produces hydroperoxides, lipoperoxides, etc.
Healthy cells have antioxidant enzymes in their cell membranes, such as: superoxide dismutase, catalase, glutathione, peroxidase, etc. There are also antioxidants such as: vitamin C, vitamin E, etc. present in the extracellular matrix fluids, plasma, etc. These antioxidants protect the healthy cells from being oxidized (burned up) by ozone.
How does ozone produce therapeutic effects in the Dental office?
Ozone is a powerful oxidant. Bacteria, Viruses, Fungi and parasites have little or no antioxidant enzymes in their cell membranes. Without this protection oxone oxidizes (burns a hole through) the cell membrane causing it to rupture, resulting in cell death. Healthy cells have antioxidant enzymes in their cell membranes and are not harmed by therapeutic levels of ozone.
Dental Applications in Endodontics
* Canals are irrigated with ozonated water to debride the canals and remove the biofilm.
* Canals are insufflated with ozone gas to eliminate pathogens and oxidize organic materials in the dentinal tubules, accessory and lateral canals.